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Supporting Research into Thrombosis

Thrombosis and pulmonary embolism (blood clots) are not uncommon and remain a global health issue, affecting thousands of people in the UK yet until Thrombosis UK (formerly known as Lifeblood: the thrombosis charity) was founded, there had been no lead independent body for thrombosis research in the UK.

Thrombosis UK continues to raise awareness of the need for research, and works with leading UK and international research institutions to inform and support on-going and new research.

Thanks to our supporters, Thrombosis UK currently assists research into multiple thrombosis studies, providing funding, generally given as seed money for small projects, but with your help, we are determined to achieve more and accelerate the progress being made in the fight against Thrombosis.

Annually, Thrombosis UK offers Research Grants and Travel Fellowships for healthcare professionals and scientists whose study will help improve the experience and outcomes of VTE patents or extend the understanding of thrombosis. Thrombosis UK cannot support projects that should be funded by the NHS.

Our Board of Trustees meets regularly to review applications. To apply please read the following Thrombosis UK documents:

Grant Application Guide Declaration of Interest

Thrombosis UK is supported by a multi-disciplinary team, who are recognised within the UK as leaders in thrombosis care and research.

Please note, successful applicants will be required to:

  • Spend any award made, on furthering their development as an expert in thrombosis
  • Submit a report on their study / research, to Thrombosis UK
  • Thrombosis UK will publish a photo of the individual with news of their grant on the Thrombosis UK website
  • Thrombosis UK reserve the right to publicise their work via Thrombosis UK social media
  • Any scientific publications from work that benefited from a Thrombosis UK grant should state that that the study was supported by Thrombosis UK and include the Thrombosis UK logo

Dr Colin Evans

Dr Colin Evans is a Postdoctoral Research Associate in the laboratory of Professor Randall Johnson at the Department of Physiology, Development and Neuroscience, University of Cambridge. His current research investigates mechanisms that regulate the strong positive association between cancer and venous thrombosis.

Dr Sian Sweetland

I am a Statistical Epidemiologist in the Cancer Epidemiology Unit, University of Oxford. My current research investigates the relationship between cancer and venous thromboembolism using questionnaire data from a large UK cohort, the Million Women Study, linked to NHS hospital admissions records, cancer registrations and deaths.

Gael Morrow

I am a 3rd Year PhD Student at the University of Aberdeen in Dr Nicola Mutch’s Lab. My PhD project has focused on determining the role of platelets in fibrinolysis (the process of breaking down a blood clot). Our laboratory has found that proteins important in fibrinolysis and coagulation are retained on the surface of activated platelets in a protruding "cap".

For over 10 years Thrombosis UK has partnered with the British Society for Haemostasis & Thrombosis (BSHT) and the British Society for Haematology (BSH) to fund a PhD research programme which is hosted by a UK university.

To date we have sponsored three students:

  • 2006-2009 - Maria Efthymiou - Activated protein C (Imperial College London – Supervised by Prof David Lane & Dr Jim Crawley)
  • 2011-1014 - Mary Underwood - ADAMTS13 and TTP (University College London – Supervised by Prof Sam Machin & Dr Ian Mackie)
  • 2015-2018 - Gael Morrow - Thrombus composition, fibrinolysis and flow (University of Aberdeen – Supervised by Dr Nikki Mutch)

 

Degradation of two novel congenital TTP ADAMTS13 mutants by the cell proteasome prevents ADAMTS13 secretion - Underwood, Peyvandi, Garagiola Machin & Mackie - Download

 

ADAMTS13 Secretion and Residual Activity among Patients with Congenital Thrombotic Thrombocytopenic Purpura with and without Renal Impairment Rurali, Banterla, Donadelli, Bresin, Galbusera, Gastoldi, Peyvandi, Underwood, Remuzzi & Marina Noris* - Download

 

Protective Effects of Non-Anticoagulant Activated Protein C Variant (D36A/L38D/ A39V) in a Murine Model of Ischaemic Stroke - Andreou, Efthymiou, Yu, Watts, Noormohamed, Ma, Lane & Crawley - Download